Alchemist Accelerator is the premiere enterprise accelerator in Silicon Valley. I’m lucky enough to be an advisor there and I wanted to share a few of the startups that recently graduated from their 2025 class. I’ve already interviewed Donkit and will most likely be bringing on a number of these startups on in the near future but until then, please check them out if you’re actively investing or looking for the best-of-the-best in Enterprise, Healthcare, and AI.

Healthcare

Arithmedics, AI Automation that Reclaims Physician Time for Patients

Why it matters: Cuts physician admin time, reduces burnout, gives patients more face time.

Cosign AI, Save months in clinical trial recruitment & never miss candidates

Why it matters: Faster enrollment shortens trials, new therapies reach patients sooner.

Polyview Health, AI agents in health care to assist providers and patients, produce marketing intelligence, and to detect fraud/waste/abuse

Why it matters: Improves care quality and reduces waste by spotting risk and fraud early.

Hera Health Solutions, A nanoscale-enabled drug delivery platform to radically improve the efficacy of existing therapeutics for pharmaceutical companies

Why it matters: Better delivery for known drugs can lift outcomes without new molecules.

Supply Chain and Manufacturing

Infis AI, We help manufacturers predict and prevent supplier disruptions by combining internal ERP data with real-time external risk signals.

Why it matters: Prevents supplier shocks, keeps lines running, protects revenue.

Kimaru AI, End supply chain chaos with adaptive real-time decisions

Why it matters: Real time decisions lower costs and delays across complex networks.

ZeeHub AI, AI transforms manufacturing supply chains into decisive action

Why it matters: Turns plant data into action, improves throughput and on time delivery.

Developer Tools

DiffEnder, Ship 2x faster with AI-Assisted Code Reviews

Why it matters: Finds bugs and risky diffs earlier, speeds safer releases.

Donkit, Donkit ends the “hundreds-of-experiments” headache of building RAG,one prompt in, production-ready pipeline out, in minutes.

Why it matters: Cuts RAG build time from weeks to minutes, de-risks production launches.

Real Estate

Besty AI, AI marketplace connecting short-term property owners with managers.

Why it matters: Raises occupancy and service quality for small owners.

Edge AI and Sensors

Kaspix, AI for 170B sensors where digital chips will never go

Why it matters: Brings AI to places chips cannot go, opens new sensing use cases.

Data and Analytics

Fuse, Your AI Data Strategist.

Why it matters: Better data planning cuts waste and lifts ROI on analytics work.

Privacy and Compliance

Melurna, Data Privacy Risk Management

Why it matters: Reduces breach and compliance risk, eases audits.

People and Market Intelligence

Pairity, Infrastructure for Understanding People

Why it matters: Clearer human insight leads to better product and policy choices.

Agriculture and Materials

Qumir Nano, We harness nanotechnology to create agricultural inputs as effective as chemicals, but with the environmental benefits of biologicals.

Why it matters: Greener inputs mean fewer chemicals and more sustainable yields.

I’m very loyal when it comes to travel backpacks. I wear them into the ground, and I usually destroy them. My last pack, a Knack Series 2, was solid, but no matter how little I put in it, it always felt too heavy because of the design and pocket layout. When a Knack zipper finally gave out, I went looking for something new.

A friend pointed me to Aer, so I picked up the Aer Travel Pack 3 Small Ultra. The “Small” designation is important because I’d say the standard size is too big. This bag holds 28 liters and weighs 3.5 pounds. It uses Ultra400X by Challenge Sailcloth, a light, waterproof fabric with a matte look. A padded, suspended pocket fits a 16-inch laptop, and the lay flat main compartment makes packing simple for clothes and shoes. You get quick access top and side pockets for small items, an expandable bottle pocket, and a hidden smart tracker pocket. Compression straps with magnetic fasteners steady the load, while load lifters, an internal framesheet, and handles on all sides keep carry comfortable and controlled. Lockable zippers add security, there are attachment points for a removable hip belt, and a luggage pass-through plays well with rolling bags. At 19 by 13 by 7.5 inches, it stays compact without feeling cramped.

I like this model because it is not too big, yet it carries a lot without dragging you down. On recent trips I fit shoes, clothes, a laptop, adapters, and a watch case without trouble. The structure helps it slide under a seat or into an overhead cleanly, and the built-in bottle holder is a real plus. The Knack lacked a bottle holder, and I missed it.

The striking part is the price, $279. It matches similar bags by size, though it sits on the high side for travel gear. Given the durability of the sailcloth, the zippers, and the thoughtful design, you can spread the cost over five years and feel fine about it. In short, you will not need to upgrade any time soon.

Aer is obviously an Instagram brand, one that follows you once you click a link, but I like the Designed in SF look, and I like the materials. It is half a pound heavier than the Knack, and I think Aer’s design and build make the whole package feel more compact and wearable. I have tested too many bags over the years, we used to run Bag Week at TechCrunch and review dozens in seven days, and this is one I plan to keep for a few years, until I finally wear it out.

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